AGICC: The Academic GI Cancer Consortium



Wells A. Messersmith, M.D.
Director of AGICC

Dr. Messersmith trained in internal medicine at Massachusetts General Hospital / Harvard Medical School and did his Medical Oncology / Drug Development Fellowship at Johns Hopkins, where he was on the faculty from 2004-2007 as Assistant Professor in the GI Oncology and Drug Development programs. He joined the University of Colorado Cancer Center in August 2007 as the Director of Gastrointestinal Medical Oncology. He was appointed co-Leader of Developmental Therapeutics in 2010, and in 2014 became Division Head of Medical Oncology, which has >50 faculty.

His focus is on clinical and translational cancer research in gastrointestinal cancers. The comprehensive GI cancer program at Colorado includes multi-disciplinary GI cancer clinics, tumor boards, and research endeavors. He has held NIH and DOD grants, and has served as the principal investigator on >60 national and local therapeutic trials. As an active investigator in the developmental therapeutics laboratory, he is working on novel targeted agents and immunotherapies as well as correlative studies for use on human tissue samples.

Dr. Messersmith is a member of multiple national committees, including the NCI Colon Cancer Task Force, National Comprehensive Cancer Network (NCCN) Committee on Colon/Rectal/Anal Cancers (which sets treatment guidelines used internationally), NCCN Investigator Steering Committee, Medical Oncology Committee of the American Board of Internal Medicine (ABIM), and others.


John S. Macdonald, M.D.
John S. Macdonald, M.D.
Senior Medical Advisor for the Oncology Consortia of Criterium

John S. Macdonald, MD, is Senior Medical Advisor for Criterium Inc. He served as Medical Director and Chief of Gastrointestinal Oncology at St. Vincent’s Comprehensive Cancer Center in New York City from 1998-2007. Dr Macdonald is Board certified in internal medicine and oncology. In addition to his responsibilities at the Saint Vincent’s Cancer Center from 1998 to 2007, Dr. Macdonald served as Chief of Medical Oncology at St. Vincent's Hospital and Medical Center, and Professor of Medicine at the New York Medical College.

Dr. Macdonald was named as the first recipient of an endowed professorship, the Lynn Wood Neag Distinguished Professor of Gastrointestinal Oncology, in 1999. He is recognized as a leading educator in Medical Oncology and has received numerous forms of recognition for his skills in medical education including being honored as Outstanding Clinical Attending Physician by the Department of Medicine at Georgetown University in 1977 and serving as a member of the Medical Oncology Section of the American Board of Internal Medicine from 1987 to 1993. Dr Macdonald served as Chair of the Gastrointestinal Cancer Committee of the Southwest Oncology Group between 1985 and 2000.

A leader in his field and a specialist in gastrointestinal cancer, Dr. Macdonald has authored more than 400 articles, abstracts and book chapters and has been published in many medical journals, including The New England Journal of Medicine, Cancer; Recent Results in Cancer Research; Advances in Medical Oncology, Research, and Education; and Medscape Hematology-Oncology. In addition to his writing he has served as editor of multiple journals including Cancer Treatment Reports, Journal of Clinical Oncology, and the Manual of Oncologic Therapeutics. In 2007 he served as editor of Advances in the Management of gastric Cancer.

Dr. Macdonald is a member of numerous professional organizations including the American College of Physicians, American Association for Cancer Research and American Society of Clinical Oncology. He has made over 400 presentations both nationally and internationally.

Dr. Macdonald received his medical degree from Harvard Medical School. He then went on to complete an internship and residency in internal medicine at the Beth Israel Hospital in Boston, and was awarded a fellowship in oncology at the National Cancer Institute. He was awarded an American Cancer Society Junior Faculty Fellowship. Dr. Macdonald was named a Fellow of the American Collage of Physicians in 1979.

Dr. Macdonald has received numerous awards and distinctions including being named in the Best Doctors in America listing in Good Housekeeping’s “Best 300 Doctors in America.” He has been named one of New York Magazine’s “Best Doctors in New York” over a seven year period.